Types of motor neuron disease?

There are several types of motor neuron disease?. The different types of motor neuron disease share similar symptoms, but they progress at different speeds and vary in severity.

These are some common types of motor neuron disease

ALS (Amyotrophic lateral sclerosis), or Lou Gehrig’s disease

It is the most common type, affecting muscles of the arms, legs, mouth, and respiratory system. Mean survival time is 3 to 5 years, but some people live 10 years or more beyond diagnosis with supportive care.

Progressive bulbar palsy (PBP)

PBP involves the brain stem. People with ALS often have PBP too. The condition causes frequent choking spells, and difficulty speaking, eating, and swallowing.

Progressive muscular atrophy (PMA)

PMA slowly but progressively causes muscle wasting, especially in the arms, legs, and mouth. It may be a variation of ALS.

Primary lateral sclerosis (PLS)


PLS is a rare form of MND that advances more slowly than ALS. It is not fatal, but it can affect the quality of life. In children, it is known as juvenile primary lateral sclerosis.

Spinal muscular atrophy (SMA)


SMA is an inherited types of motor neuron disease that affects children. There are three types, all caused by an abnormal gene known as SMA1. It tends to affect the trunk, legs, and arms. The long-term outlook varies according to type.

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